作者
Prateek J Khatri, John G Webb, Josep Rodés-Cabau, Stephen E Fremes, Marc Ruel, Kelly Lau, Helen Guo, Harindra C Wijeysundera, Dennis T Ko
发表日期
2013/1/1
来源
Annals of internal medicine
卷号
158
期号
1
页码范围
35-46
出版商
American College of Physicians
简介
Background
Transcatheter aortic valve implantation (TAVI) has emerged as an important treatment for patients with severe symptomatic aortic stenosis who are at high operative risk, but accurate estimates of serious adverse effects in contemporary practice are not available.
Purpose
To quantify the adverse effects associated with TAVI, and to evaluate whether the type of transcatheter valve and the route of valve implantation are associated with differences in adverse outcomes.
Data Source
PubMed to 5 May 2012.
Study Selection
All studies that included at least 100 patients who had TAVI and reported at least 1 outcome of interest.
Data Extraction
Two reviewers abstracted the data independently. A random-effects model was used to combine data on adverse outcomes …
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