作者
Agnieszka Lemanska, Colm Andrews, Louis Fisher, Seb Bacon, Amir Mehrkar, Peter Inglesby, Simon Davy, Ben Goldacre, Brian MacKenna, OpenSAFELY Collaborative, Alex J Walker, Christopher T Rentsch, Helen J Curtis, Caroline E Morton, Jessica Morley, George Hickman, Chris Bates, Richard Croker, David Evans, Tom Ward, Jonathan Cockburn, Krishnan Bhaskaran, Anna Schultze, Elizabeth J Williamson, William J Hulme, Helen I McDonald, Laurie Tomlinson, Rohini Mathur, Rosalind M Eggo, Kevin Wing, Angel YS Wong, Harriet Forbes, John Tazare, John Parry, Frank Hester, Sam Harper, Ian J Douglas, Stephen JW Evans, Liam Smeeth
发表日期
2024/2/27
期刊
BJU international
简介
Objectives
To investigate the effect of the COVID‐19 pandemic on prostate cancer incidence, prevalence, and mortality in England.
Patients and Methods
With the approval of NHS England and using the OpenSAFELY‐TPP dataset of 24 million patients, we undertook a cohort study of men diagnosed with prostate cancer. We visualised monthly rates in prostate cancer incidence, prevalence, and mortality per 100 000 adult men from January 2015 to July 2023. To assess the effect of the pandemic, we used generalised linear models and the pre‐pandemic data to predict the expected rates from March 2020 as if the pandemic had not occurred. The 95% confidence intervals (CIs) of the predicted values were used to estimate the significance of the difference between the predicted and observed rates.
Results
In 2020, there was a drop in recorded incidence by 4772 (31%) cases (15 550 vs 20 322; 95% CI 19 …
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A Lemanska, C Andrews, L Fisher, S Bacon, A Mehrkar… - BJU international, 2024