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Salmonellosis is a typical zoonotic disease that occurs frequently in poultry flocks. Many salmonella serovars have been found to be responsible for this disease. In this review besides, poultry as a carrier of Salmonella enterica serovar Typhimurium infection, various infectious routes, pathology, sources of infection are discussed as well as diagnostic measures and preventive strategies that aim at reducing the incidence of salmonellosis at the farm level. Among the different diseases occurring in poultry, those caused by the genus Salmonella is the most common, causing serious losses to the poultry industry in terms of mortality, reduced growth and loss of egg production. The diseases caused by S. enterica serovar Typhimurium have got public health significance, as well as being associated with food poisoning in humans. Salmonellosis in humans is mainly caused by S. typhimurium. The ability of this serovar to …