作者
Brian A Bergmark, Deepak L Bhatt, Eugene Braunwald, David A Morrow, Ph Gabriel Steg, Yared Gurmu, Avivit Cahn, Ofri Mosenzon, Itamar Raz, Erin Bohula, Benjamin M Scirica
发表日期
2018/3/1
期刊
Diabetes Care
卷号
41
期号
3
页码范围
577-585
出版商
American Diabetes Association
简介
OBJECTIVE
Improved risk assessment for patients with type 2 diabetes and elevated cardiovascular (CV) risk is needed. The Thrombolysis in Myocardial Infarction (TIMI) Risk Score for Secondary Prevention (TRS 2°P) predicts a gradient of risk in patients with prior myocardial infarction (MI) but has not been evaluated in patients with type 2 diabetes.
RESEARCH DESIGN AND METHODS
CV event rates were compared by baseline TRS 2°P in 16,488 patients enrolled in SAVOR-TIMI 53 (Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus–Thrombolysis in Myocardial Infarction 53) with type 2 diabetes and high CV risk or established CV disease. Calibration was tested in the diabetes cohort from the REACH (REduction of Atherothrombosis for Continued Health) Registry.
RESULTS
TRS 2°P revealed a robust risk gradient …
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BA Bergmark, DL Bhatt, E Braunwald, DA Morrow… - Diabetes Care, 2018