作者
Marc S Sabatine, Brian A Bergmark, Sabina A Murphy, Patrick T O'Gara, Peter K Smith, Patrick W Serruys, A Pieter Kappetein, Seung-Jung Park, Duk-Woo Park, Evald H Christiansen, Niels R Holm, Per H Nielsen, Gregg W Stone, Joseph F Sabik, Eugene Braunwald
发表日期
2021/12/18
来源
The Lancet
卷号
398
期号
10318
页码范围
2247-2257
出版商
Elsevier
简介
Background
The optimal revascularisation strategy for patients with left main coronary artery disease is uncertain. We therefore aimed to evaluate long-term outcomes for patients treated with percutaneous coronary intervention (PCI) with drug-eluting stents versus coronary artery bypass grafting (CABG).
Methods
In this individual patient data meta-analysis, we searched MEDLINE, Embase, and the Cochrane database using the search terms "left main", "percutaneous coronary intervention" or "stent", and "coronary artery bypass graft*" to identify randomised controlled trials (RCTs) published in English between database inception and Aug 31, 2021, comparing PCI with drug-eluting stents with CABG in patients with left main coronary artery disease that had at least 5 years of patient follow-up for all-cause mortality. Two authors (MSS and BAB) identified studies meeting the criteria. The primary endpoint was 5-year all …
引用总数