作者
Young-Ki Bae, Shuichi Kani, Takashi Shimizu, Koji Tanabe, Hideaki Nojima, Yukiko Kimura, Shin-ichi Higashijima, Masahiko Hibi
发表日期
2009/6/15
期刊
Developmental biology
卷号
330
期号
2
页码范围
406-426
出版商
Academic Press
简介
The cerebellum is important for the integration of sensory perception and motor control, but its structure has mostly been studied in mammals. Here, we describe the cell types and neural tracts of the adult zebrafish cerebellum using molecular markers and transgenic lines. Cerebellar neurons are categorized to two major groups: GABAergic and glutamatergic neurons. The Purkinje cells, which are GABAergic neurons, express parvalbumin7, carbonic anhydrase 8, and aldolase C like (zebrin II). The glutamatergic neurons are vglut1+ granule cells and vglut2high cells, which receive Purkinje cell inputs; some vglut2high cells are eurydendroid cells, which are equivalent to the mammalian deep cerebellar nuclei. We found olig2+ neurons in the adult cerebellum and ascertained that at least some of them are eurydendroid cells. We identified markers for climbing and mossy afferent fibers, efferent fibers, and parallel …
引用总数
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