作者
Ander Ramos‐Murguialday, Doris Broetz, Massimiliano Rea, Leonhard Läer, Özge Yilmaz, Fabricio L Brasil, Giulia Liberati, Marco R Curado, Eliana Garcia‐Cossio, Alexandros Vyziotis, Woosang Cho, Manuel Agostini, Ernesto Soares, Surjo Soekadar, Andrea Caria, Leonardo G Cohen, Niels Birbaumer
发表日期
2013/7
期刊
Annals of neurology
卷号
74
期号
1
页码范围
100-108
简介
Objective
Chronic stroke patients with severe hand weakness respond poorly to rehabilitation efforts. Here, we evaluated efficacy of daily brain–machine interface (BMI) training to increase the hypothesized beneficial effects of physiotherapy alone in patients with severe paresis in a double‐blind sham‐controlled design proof of concept study.
Methods
Thirty‐two chronic stroke patients with severe hand weakness were randomly assigned to 2 matched groups and participated in 17.8 ± 1.4 days of training rewarding desynchronization of ipsilesional oscillatory sensorimotor rhythms with contingent online movements of hand and arm orthoses (experimental group, n = 16). In the control group (sham group, n = 16), movements of the orthoses occurred randomly. Both groups received identical behavioral physiotherapy immediately following BMI training or the control intervention. Upper limb motor function …
学术搜索中的文章
A Ramos‐Murguialday, D Broetz, M Rea, L Läer… - Annals of neurology, 2013