作者
Martin Lotze, Pedro Montoya, Michael Erb, Ernst Hülsmann, Herta Flor, Uwe Klose, Niels Birbaumer, Wolfgang Grodd
发表日期
1999/9/1
期刊
Journal of cognitive neuroscience
卷号
11
期号
5
页码范围
491-501
出版商
MIT Press
简介
Brain activation during executed (EM) and imagined movements (IM) of the right and left hand was studied in 10 healthy right-handed subjects using functional magnetic resonance imagining (fMRI). Low electromyographic (EMG) activity of the musculi flexor digitorum superficialis and high vividness of the imagined movements were trained prior to image acquisition. Regional cerebral activation was measured by fMRI during EM and IM and compared to resting conditions. Anatomically selected regions of interest (ROIs) were marked interactively over the entire brain. In each ROI activated pixels above a t value of 2.45 (p < 0.01) were counted and analyzed. In all subjects the supplementary motor area (SMA), the premotor cortex (PMC), and the primary motor cortex (M1) showed significant activation during both EM and IM; the somatosensory cortex (S1) was significantly activated only during EM. Ipsilateral …
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M Lotze, P Montoya, M Erb, E Hülsmann, H Flor… - Journal of cognitive neuroscience, 1999