作者
Niels Birbaumer, Leonardo G Cohen
发表日期
2007/3/15
来源
The Journal of physiology
卷号
579
期号
3
页码范围
621-636
出版商
Blackwell Publishing Ltd
简介
The review describes the status of brain–computer or brain–machine interface research. We focus on non‐invasive brain–computer interfaces (BCIs) and their clinical utility for direct brain communication in paralysis and motor restoration in stroke. A large gap between the promises of invasive animal and human BCI preparations and the clinical reality characterizes the literature: while intact monkeys learn to execute more or less complex upper limb movements with spike patterns from motor brain regions alone without concomitant peripheral motor activity usually after extensive training, clinical applications in human diseases such as amyotrophic lateral sclerosis and paralysis from stroke or spinal cord lesions show only limited success, with the exception of verbal communication in paralysed and locked‐in patients. BCIs based on electroencephalographic potentials or oscillations are ready to undergo large …
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