作者
Gowri Raman, Denish Moorthy, Nira Hadar, Issa J Dahabreh, Thomas F O'Donnell, David E Thaler, Edward Feldmann, Joseph Lau, Georgios D Kitsios
发表日期
2013/5/7
来源
Annals of internal medicine
卷号
158
期号
9
页码范围
676-685
出版商
American College of Physicians
简介
Background
Adults with asymptomatic carotid artery stenosis are at increased risk for ipsilateral carotid territory ischemic stroke.
Purpose
To examine comparative evidence on management strategies for asymptomatic carotid stenosis and the incidence of ipsilateral stroke with medical therapy alone.
Data Sources
MEDLINE, Cochrane Central Register of Controlled Trials, U.S. Food and Drug Administration documents, and review of references through 31 December 2012.
Study Selection
Randomized, controlled trials (RCTs) and prospective or retrospective nonrandomized, comparative studies of medical therapy alone, carotid endarterectomy (CEA) plus medical therapy, or carotid artery stenting (CAS) plus medical therapy for adults with asymptomatic carotid stenosis, as well as single-group prospective …
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