作者
Andrés Esteban, Niall D Ferguson, Maureen O Meade, Fernando Frutos-Vivar, Carlos Apezteguia, Laurent Brochard, Konstantinos Raymondos, Nicolas Nin, Javier Hurtado, Vinko Tomicic, Marco González, José Elizalde, Peter Nightingale, Fekri Abroug, Paolo Pelosi, Yaseen Arabi, Rui Moreno, Manuel Jibaja, Gabriel D'Empaire, Fredi Sandi, Dimitros Matamis, Ana María Montañez, Antonio Anzueto
发表日期
2008/1/15
来源
American journal of respiratory and critical care medicine
卷号
177
期号
2
页码范围
170-177
出版商
American Thoracic Society
简介
Rationale: Recent literature in mechanical ventilation includes strong evidence from randomized trials. Little information is available regarding the influence of these trials on usual clinical practice.
Objectives: To describe current mechanical ventilation practices and to assess the influence of interval randomized trials when compared with findings from a 1998 cohort.
Methods: A prospective international observational cohort study, with a nested comparative study performed in 349 intensive care units in 23 countries. We enrolled 4,968 consecutive patients receiving mechanical ventilation over a 1-month period. We recorded demographics and daily data related to mechanical ventilation for the duration of ventilation. We systematically reviewed the literature and developed 11 practice-change hypotheses for the comparative cohort study before seeing these results. In assessing practice changes, we only compared …
引用总数
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A Esteban, ND Ferguson, MO Meade, F Frutos-Vivar… - American journal of respiratory and critical care …, 2008