作者
Omar Y Tammam, Mahmoud A Elrehany, Faten AM Abo-Aziza, Shereen S Gaber, Asmaa Bayoumi
发表日期
2021/7/1
期刊
Minia Journal of Medical Research
卷号
32
期号
3
页码范围
1-3
出版商
Minia University, Faculty of Medicine
简介
Background
The liver is one of the most important organs in the human body because of its utmost importance, and it plays many essential roles for the body. Carbon tetrachloride affects the body in general and the liver, which sometimes leads to the occurrence of chronic hepatitis and may reach its climax and cause fibrosis. One of the effects of carbon tetrachloride is the stimulation of the beta-TGF pathway.
Results
After CCL4 administration; There is highly statistically significant difference in expression level of TGF-β (p < 0.005).
Conclusions
This study shows that carbon tetra chloride is promotor for several liver diseases that occur due to activation and upregulation of TGF-β.
学术搜索中的文章
OY Tammam, MA Elrehany, FAM Abo-Aziza, SS Gaber… - Minia Journal of Medical Research, 2021