查看文章

Objective To identify whether measures of childhood physical control and coordination as markers of neurological function are associated with obesity in adults.

Design Longitudinal birth cohort study.

Setting National child development study in Great Britain.

Participants 11 042 people born during one week in 1958.

Main outcome measure Obesity at age 33 years defined as body mass index ≥30.

Results Among 7990 cohort members at age 7 years, teachers reported that poor hand control, poor coordination, and clumsiness “certainly applied” more often among those who would be obese adults, producing adjusted odds ratios of 1.57 (95% confidence interval 1.13 to 2.20; P=0.008) for poor hand control, 2.30 (1.52 to 3.46; P<0.001) for poor coordination, and 3.91 (2.61 to 5.87; P<0.001) for clumsiness. Among 6875 participants who had doctor administered assessments with continuous scores at age 11 years …