作者
Marlou-Floor Kenkhuis, Mo Klingestijn, Anne-Marie Fanshawe, Stéphanie O Breukink, Maryska LG Janssen-Heijnen, Eric TP Keulen, Sabina Rinaldi, Paolo Vineis, Marc J Gunter, Michael F Leitzmann, Augustin Scalbert, Matty P Weijenberg, Martijn JL Bours, Eline H van Roekel
发表日期
2022/8/30
期刊
Journal of Cancer Research and Clinical Oncology
页码范围
1-13
出版商
Springer Berlin Heidelberg
简介
Purpose
We investigated longitudinal associations of sedentary behavior, light-intensity physical activity (LPA) and moderate-to-vigorous physical activity (MVPA) with body composition in colorectal cancer (CRC) survivors, between 6 weeks and 24 months post treatment. In addition, we explored whether body composition mediated associations of sedentary behavior and MVPA with fatigue.
Methods
A prospective cohort study was conducted in 459 stage I–III CRC patients recruited at diagnosis. Measurements were performed of accelerometer-assessed sedentary time (hours/day), self-reported LPA and MVPA (hours/week), anthropometric assessment of body mass index (BMI), waist circumference and fat percentage (measures of adiposity), and muscle circumference and handgrip strength (measures of muscle mass/function) repeated at 6 weeks, and 6, 12 and 24 months post treatment. Longitudinal associations …
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