作者
Nadira R Querido, Marlou Floor Kenkhuis, Eline H van Roekel, Stéphanie O Breukink, Fränzel J B van Duijnhoven, Maryska LG Janssen-Heijnen, Eric TP Keulen, Per Magne Ueland, F Jeroen Vogelaar, Evertine Wesselink, Martijn JL Bours, Matty P Weijenberg
发表日期
2022/6/2
期刊
Cancer Epidemiology, Biomarkers & Prevention
简介
Background
Fatigue is often reported by colorectal cancer survivors and largely impacts their quality of life. Inflammation has been linked to fatigue mainly in patients with breast cancer. Therefore, we investigated how inflammation is longitudinally associated with fatigue in colorectal cancer survivors, up to 2 years posttreatment.
Methods
A total of 257 patients from the ongoing Energy for life after ColoRectal cancer cohort study were included in the analysis. Plasma levels of IL6, IL8, IL10, TNFα, high-sensitivity C-reactive protein (hsCRP), and fatigue were measured at 6 weeks, 6, 12, and 24 months posttreatment. Fatigue was measured through the validated Checklist Individual Strength (CIS; total, 20–140), consisting of four subscales – subjective fatigue (8–), motivation , physical activity , and concentration , and the European Organisation for Research and Treatment of …
学术搜索中的文章
NR Querido, MF Kenkhuis, EH Van Roekel… - Cancer Epidemiology, Biomarkers & Prevention, 2022