作者
Myles C Murphy, Christopher Latella, Ebonie K Rio, Janet L Taylor, Stephanie Martino, Colin Sylvester, William Hale, Andrea B Mosler
发表日期
2023/12/1
来源
EFORT Open Reviews
卷号
8
期号
12
页码范围
883-894
出版商
Bioscientifica Ltd
简介
Purpose
  • The aim of the study was to quantify motor cortex descending drive and voluntary activation (VA) in people with lower-limb OA compared to controls.
Methods
  • A systematic review and meta-analysis according to the PRISMA guidelines was carried out. Seven databases were searched until 30 December 2022. Studies assessing VA or responses to transcranial magnetic stimulation (TMS; i.e. motor evoked potential, intracortical facilitation, motor threshold, short-interval intracortical inhibition, and silent period) were included. Study quality was assessed using Joanna Briggs Institute criteria and evidence certainty using GRADE. The meta-analysis was performed using RevMan inverse variance, mixed-effect models.
Results
  • Eighteen studies were included, all …
引用总数
20242
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