作者
Jo Annika Reins, Claudia Buntrock, Johannes Zimmermann, Simon Grund, Mathias Harrer, Dirk Lehr, Harald Baumeister, Kiona Weisel, Matthias Domhardt, Kotaro Imamura, Norito Kawakami, Viola Spek, Stephanie Nobis, Frank Snoek, Pim Cuijpers, Jan Philipp Klein, Steffen Moritz, David Daniel Ebert
发表日期
2021/2/18
期刊
Psychotherapy and Psychosomatics
卷号
90
期号
2
页码范围
94-106
出版商
S. Karger AG
简介
Introduction
Evidence on effects of Internet-based interventions to treat subthreshold depression (sD) and prevent the onset of major depression (MDD) is inconsistent.
Objective
We conducted an individual participant data meta-analysis to determine differences between intervention and control groups (IG, CG) in depressive symptom severity (DSS), treatment response, close to symptom-free status, symptom deterioration and MDD onset as well as moderators of intervention outcomes.
Methods
Randomized controlled trials were identified through systematic searches via PubMed, PsycINFO, Embase and Cochrane Library. Multilevel regression analyses were used to examine efficacy and moderators.
Results
Seven trials (2,186 participants) were included. The IG was superior in DSS at all measurement points (posttreatment: 6–12 weeks; Hedges’g= 0.39 [95% CI: 0.25–0.53]; follow-up 1: 3–6 months; g= 0.30 [95 …
引用总数
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