作者
Doff B McElhinney, Lars Sondergaard, Aimee K Armstrong, Lisa Bergersen, Robert F Padera, David T Balzer, Te-Hsin Lung, Felix Berger, Evan M Zahn, Robert G Gray, William E Hellenbrand, Jacqueline Kreutzer, Andreas Eicken, Thomas K Jones, Peter Ewert
发表日期
2018/12/4
期刊
Journal of the American College of Cardiology
卷号
72
期号
22
页码范围
2717-2728
出版商
American College of Cardiology Foundation
简介
Background
Endocarditis has emerged as one of the most concerning adverse outcomes in patients with congenital anomalies involving the right ventricular outflow tract (RVOT) and prosthetic valves.
Objectives
The aim of this study was to evaluate rates and potential risk factors for endocarditis after transcatheter pulmonary valve replacement in the prospective Melody valve trials.
Methods
All patients in whom a transcatheter pulmonary valve (TPV) was implanted in the RVOT as part of 3 prospective multicenter studies comprised the analytic cohort. The diagnosis of endocarditis and involvement of the TPV were determined by the implanting investigator.
Results
A total of 309 patients underwent transcatheter pulmonary valve replacement (TPVR) and were discharged with a valve in place. The median follow-up duration was 5.1 years, and total observation until study exit was 1,660.3 patient-years. Endocarditis was …
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DB McElhinney, L Sondergaard, AK Armstrong… - Journal of the American College of Cardiology, 2018