作者
Lídia Bofill, Rafael Barbas, Dafne de Sande, Mercè Font-Bardia, Clara Rafols, Joan Albertí, Rafel Prohens
发表日期
2021/3/3
期刊
Crystal Growth & Design
卷号
21
期号
4
页码范围
2315-2323
出版商
American Chemical Society
简介
New multicomponent solid forms of the nutraceutical pterostilbene have been discovered and characterized through experimental cocrystal screening. Among the coformers tested, picolinic acid formed a cocrystal with a 10-fold enhancement of oral bioavailability in rats, which converts the new cocrystal into a very promising candidate for new formulations of pterostilbene with improved performance.
学术搜索中的文章
L Bofill, R Barbas, D de Sande, M Font-Bardia… - Crystal Growth & Design, 2021