作者
Christopher M Cielo, Jesse A Taylor, Arastoo Vossough, Jerilynn Radcliffe, Allison Thomas, Ruth Bradford, Janet Lioy, Ignacio E Tapia, Reza Assadsangabi, Justine Shults, Carole L Marcus
发表日期
2016/7/15
期刊
Journal of Clinical Sleep Medicine
卷号
12
期号
7
页码范围
979-987
出版商
American Academy of Sleep Medicine
简介
Study Objectives
Children with craniofacial anomalies are a heterogeneous group at high risk for obstructive sleep apnea (OSA). However, the prevalence and structural predictors of OSA in this population are unknown. We hypothesized that infants with micrognathia would have more significant OSA than those with isolated cleft palate ± cleft lip (ICP), and those with ICP would have more significant OSA than controls. We postulated that OSA severity would correlate with reduced mandibular size, neurodevelopmental scores, and growth.
Methods
Prospective cohort study. 15 infants with ICP, 19 with micrognathia, and 9 controls were recruited for polysomnograms, neurodevelopmental testing, cephalometrics (ICP and micrognathia groups) at baseline and a follow-up at 6 mo.
Results
Baseline apnea-hypopnea index (AHI) [median (range)] of the micrognathia group [20.1 events/h (0.8, 54.7)] was greater than ICP [3.2 …
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CM Cielo, JA Taylor, A Vossough, J Radcliffe… - Journal of Clinical Sleep Medicine, 2016