作者
G Foffani, AM Bianchi, Giuseppe Baselli, A Priori
发表日期
2005/10
期刊
The Journal of physiology
卷号
568
期号
2
页码范围
699-711
出版商
Blackwell Science Ltd
简介
Event‐related changes of brain electrical rhythms are typically analysed as amplitude modulations of local field potential (LFP) oscillations, like radio amplitude modulation broadcasting. In telecommunications, frequency modulation (FM) is less susceptible to interference than amplitude modulation (AM) and is therefore preferred for high‐fidelity transmissions. Here we hypothesized that LFP rhythms detected from deep brain stimulation (DBS) electrodes implanted in the subthalamic nucleus (STN) in patients with Parkinson's disease could represent movement‐related activity not only in AM but also in FM. By combining adaptive autoregressive identification with spectral power decomposition, we were able to show that FM of low‐beta (13–20 Hz) and high‐beta (20–35 Hz) rhythms significantly contributes to the involvement of the human STN in movement preparation, execution and recovery, and that the FM …
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