作者
Holly Tuokko, Robert Frerichs, Janice Graham, Kenneth Rockwood, Betsy Kristjansson, John Fisk, Howard Bergman, Al Kozma, Ian McDowell
发表日期
2003/4/1
期刊
Archives of neurology
卷号
60
期号
4
页码范围
577-582
出版商
American Medical Association
简介
Context
The importance of early identification of dementia has prompted numerous investigations of mild cognitive impairment and the preclinical stages of progressive degenerative disorders. To date, there is limited information from large-scale studies regarding outcomes of persons specifically identified with cognitive impairment but no dementia (CIND).
Objectives
To investigate outcomes for persons with no cognitive impairment (NCI) or CIND, focusing on its etiologic subcategories, from the Canadian Study of Health and Aging (CSHA) and to examine the predictive validity of a set of core features thought to be early manifestations of subsequent dementia.
Design
Five-year, longitudinal follow-up of all persons without dementia examined during the first phase of the CSHA in 1991.
Setting
Community and institutional settings.
Participants
Population-based sample of 883 persons with NCI and 801 persons with CIND …
引用总数
学术搜索中的文章
H Tuokko, R Frerichs, J Graham, K Rockwood… - Archives of neurology, 2003