作者
Deepak P Patil, Dhiraj P Dhotre, Sachin G Chavan, Armiya Sultan, Dhawal S Jain, Vikram B Lanjekar, Jayshree Gangawani, Poonam S Shah, Jayshree S Todkar, Shashank Shah, Dilip R Ranade, Milind S Patole, Yogesh S Shouche
发表日期
2012/9
期刊
Journal of biosciences
卷号
37
页码范围
647-657
出版商
Springer-Verlag
简介
Obesity is a consequence of a complex interplay between the host genome and the prevalent obesogenic factors among the modern communities. The role of gut microbiota in the pathogenesis of the disorder was recently discovered; however, 16S-rRNA-based surveys revealed compelling but community-specific data. Considering this, despite unique diets, dietary habits and an uprising trend in obesity, the Indian counterparts are poorly studied. Here, we report a comparative analysis and quantification of dominant gut microbiota of lean, normal, obese and surgically treated obese individuals of Indian origin. Representative gut microbial diversity was assessed by sequencing fecal 16S rRNA libraries for each group (n = 5) with a total of over 3000 sequences. We detected no evident trend in the distribution of the predominant bacterial phyla, Bacteroidetes and Firmicutes. At the genus level, the bacteria …
引用总数
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学术搜索中的文章
DP Patil, DP Dhotre, SG Chavan, A Sultan, DS Jain… - Journal of biosciences, 2012