作者
Richard A Gibbs, Jeffrey Rogers, Michael G Katze, Roger Bumgarner, George M Weinstock, Elaine R Mardis, Karin A Remington, Robert L Strausberg, J Craig Venter, Richard K Wilson, Mark A Batzer, Carlos D Bustamante, Evan E Eichler, Matthew W Hahn, Ross C Hardison, Kateryna D Makova, Webb Miller, Aleksandar Milosavljevic, Robert E Palermo, Adam Siepel, James M Sikela, Tony Attaway, Stephanie Bell, Kelly E Bernard, Christian J Buhay, Mimi N Chandrabose, Marvin Dao, Clay Davis, Kimberly D Delehaunty, Yan Ding, Huyen H Dinh, Shannon Dugan-Rocha, Lucinda A Fulton, Ramatu Ayiesha Gabisi, Toni T Garner, Jennifer Godfrey, Alicia C Hawes, Judith Hernandez, Sandra Hines, Michael Holder, Jennifer Hume, Shalini N Jhangiani, Vandita Joshi, Ziad Mohid Khan, Ewen F Kirkness, Andrew Cree, R Gerald Fowler, Sandra Lee, Lora R Lewis, Zhangwan Li, Yih-shin Liu, Stephanie M Moore, Donna Muzny, Lynne V Nazareth, Dinh Ngoc Ngo, Geoffrey O Okwuonu, Grace Pai, David Parker, Heidie A Paul, Cynthia Pfannkoch, Craig S Pohl, Yu-Hui Rogers, San Juana Ruiz, Aniko Sabo, Jireh Santibanez, Brian W Schneider, Scott M Smith, Erica Sodergren, Amanda F Svatek, Teresa R Utterback, Selina Vattathil, Wesley Warren, Courtney Sherell White, Asif T Chinwalla, Yucheng Feng, Aaron L Halpern, LaDeana W Hillier, Xiaoqiu Huang, Pat Minx, Joanne O Nelson, Kymberlie H Pepin, Xiang Qin, Granger G Sutton, Eli Venter, Brian P Walenz, John W Wallis, Kim C Worley, Shiaw-Pyng Yang, Steven M Jones, Marco A Marra, Mariano Rocchi, Jacqueline E Schein, Robert Baertsch, Laura Clarke, Miklós Csürös, Jarret Glasscock, R Alan Harris, Paul Havlak, Andrew R Jackson, Huaiyang Jiang, Yue Liu, David N Messina, Yufeng Shen, Henry Xing-Zhi Song, Todd Wylie, Lan Zhang, Ewan Birney, Kyudong Han, Miriam K Konkel, Jungnam Lee, Arian FA Smit, Brygg Ullmer, Hui Wang, Jinchuan Xing, Richard Burhans, Ze Cheng, John E Karro, Jian Ma, Brian Raney, Xinwei She, Michael J Cox, Jeffery P Demuth, Laura J Dumas, Sang-Gook Han, Janet Hopkins, Anis Karimpour-Fard, Young H Kim, Jonathan R Pollack, Tomas Vinar, Charles Addo-Quaye, Jeremiah Degenhardt, Alexandra Denby, Melissa J Hubisz, Amit Indap, Carolin Kosiol, Bruce T Lahn, Heather A Lawson, Alison Marklein, Rasmus Nielsen, Eric J Vallender, Andrew G Clark, Betsy Ferguson, Ryan D Hernandez, Kashif Hirani, Hildegard Kehrer-Sawatzki, Jessica Kolb, Shobha Patil, Ling-Ling Pu, Yanru Ren, David Glenn Smith
发表日期
2007/4/13
期刊
Science
卷号
316
期号
5822
页码范围
222-234
出版商
American Association for the Advancement of Science
简介
The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and physiologically similar to humans, rhesus monkeys are the most widely used nonhuman primate in basic and applied biomedical research. We determined the genome sequence of an Indian-origin Macaca mulatta female and compared the data with chimpanzees and humans to reveal the structure of ancestral primate genomes and to identify evidence for positive selection and lineage-specific expansions and contractions of gene families. A comparison of sequences from individual animals was used to investigate their underlying genetic diversity. The complete description of the macaque genome blueprint enhances the utility of this animal model for biomedical research and improves our understanding of the basic biology of the …
引用总数
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