作者
Francesco Bartoli, Giuseppe Carrà, Giulia Brambilla, Daniele Carretta, Cristina Crocamo, Julia Neufeind, Alex Baldacchino, Gerry Humphris, Massimo Clerici
发表日期
2014/1/1
来源
Drug and alcohol dependence
卷号
134
页码范围
12-21
出版商
Elsevier
简介
Background
Assessing factors associated with non-fatal overdose is important as these could be useful to identify individuals with substance use disorders at high risk of adverse outcomes and consequences. Depression may play an important role in terms of overdose risk. We aimed to test if drug users suffering from a depressive disorder might have significantly higher risk of non-fatal overdose as compared with drug users without depression.
Methods
We conducted a systematic review and meta-analysis. PubMed, Embase and Web of Knowledge were searched. The pooled analyses were based on prevalence rates, risk difference (RD) and odds ratio (OR), reporting 95% confidence intervals (CIs). The combined estimates were obtained weighting each study according to random effects model for meta-analysis.
Results
Seven articles, involving 12,019 individuals, and run in the US, Canada, Sweden, Norway …
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