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In Ethiopia, an array of measures have been adopted to control the rapid spread of the Coronavirus Disease 2019 (COVID-19) pandemic. Such control measures could significantly influence the knowledge, attitudes, and practices (KAP) towards COVID-19 in the general population. However, still, there is scarce information regarding the KAP of students towards the COVID-19 pandemic. Therefore, this study aimed to assess KAP and associated factors towards COVID-19 among secondary school students in Gondar town, Ethiopia.

A cross-sectional study was conducted from February to April 2021 on a total of 395 participants. Proportional sample allocation was used in 4 randomly selected schools. Then, students from each of the schools were recruited by using a systematic random sampling technique. Socio-demographic data and questions regarding the KAP were collected via a self-administered questionnaire. Statistical analysis was performed by using SPSS 20. Logistic regression analyses were used to identify the associated factors and p-value <0.05 was considered statistically significant.

The mean age of study participants was 17.7±1.5 years and slightly more than 2/3 (67.3%) ranges from 17–19 years old. In this study, 86.3% (95% CI: 83–90) of study participants had good knowledge about COVID-19. Students having urban residence (AOR, with 95% CI: 5.6 (1.76–17.6), fathers with a diploma and above educational status (AOR, with 95% CI: 3 (1.2–7.5), and uses television or radio as a source of information (AOR, with 95% CI: 3.7 (1.5–9.3) tended to have good knowledge about COVID-19. About …