作者
Matheus D Baldissera, Nathieli B Bottari, Ricardo E Mendes, Claiton I Schwertz, Neuber J Lucca, Diessica Dalenogare, Guilherme V Bochi, Rafael N Moresco, Vera M Morsch, Maria RC Schetinger, Virginia C Rech, Jeandre A Jaques, Aleksandro S Da Silva
发表日期
2015/11/1
期刊
Pathology-Research and Practice
卷号
211
期号
11
页码范围
871-876
出版商
Urban & Fischer
简介
The aim of this study was to investigate acetylcholinesterase (AChE) in total blood and liver tissue; butyrylcholinesterase (BChE) in serum and liver tissue; adenosine deaminase (ADA) in serum and liver tissue; and pyruvate kinase (PK) in liver tissue of rats experimentally infected by Fasciola hepatica. Animals were divided into two groups with 12 animals each, as follows: group A (uninfected) and group B (infected). Samples were collected at 20 (A1 and B1; n = 6 each) and 150 (A2 and B2; n = 6 each) days post-infection (PI). Infected animals showed an increase in AChE activity in whole blood and a decrease in AChE activity in liver homogenates (P < 0.05) at 20 and 150 days PI. BChE and PK activities were decreased (P < 0.05) in serum and liver homogenates of infected animals at 150 days PI. ADA activity was decreased in serum at 20 and 150 days PI, while in liver homogenates it was only decreased at 150 …
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MD Baldissera, NB Bottari, RE Mendes, CI Schwertz… - Pathology-Research and Practice, 2015