作者
Younga H Lee, George D Papandonatos, David A Savitz, William C Heindel, Stephen L Buka
发表日期
2020/1
期刊
Paediatric and perinatal epidemiology
卷号
34
期号
1
页码范围
70-79
简介
Background
Previous epidemiologic studies have reported adverse neurodevelopmental sequelae following prenatal infectious exposure, yet long‐term effects estimated from these observational studies are often subject to biases due to confounding and loss to follow‐up.
Objectives
We demonstrate the joint use of inverse probability (IP) treatment and censoring weights when evaluating neurotoxic effects of prenatal bacterial infection.
Methods
We applied IP weighting for both treatment and censoring to estimate the effects of maternal bacterial infection during pregnancy on mean intelligence quotient (IQ) scores measured at age 7 using the Wechsler Intelligence Scale for Children. Participants were members of a population‐based pregnancy cohort recruited in the Boston and Providence sites of the Collaborative Perinatal Project between 1959 and 1966 (n = 11 984). We calculated average treatment effects …
引用总数
2020202120222023202411861
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YH Lee, GD Papandonatos, DA Savitz, WC Heindel… - Paediatric and perinatal epidemiology, 2020