作者
Rehab Badawi, Muhammad N Asghar, Sherief Abd-Elsalam, Samah A Elshweikh, Tamer Haydara, Sherein M Alnabawy, Mahmoud Elkadeem, Walaa ElKhalawany, Samah Soliman, Reham Elkhouly, Shimaa Soliman, Mona Watany, Mai Khalif, Asem Elfert
发表日期
2020/6/1
期刊
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Inflammatory and Anti-Allergy Agents)
卷号
19
期号
2
页码范围
140-148
出版商
Bentham Science Publishers
简介
Background
Diagnosis of Spontaneous Bacterial Peritonitis (SBP) depends mainly on ascetic fluid culture which may be negative in spite of the clinical suggestion of SBP and high ascetic fluid neutrophilic count.
Aims
This study aimed to evaluate the biological importance of amyloid A biomarker in both serum and ascetic fluid to diagnose SBP as early as possible and to compare it to other markers (C-reactive protein (CRP), and the neutrophil-to-lymphocyte ratio (NLR)).
Methods
This study included 37 patients with hepatic ascites; twenty-two of them had SBP, and 15 patients did not have SBP. Serum and ascetic fluid amyloid A, ascetic fluid neutrophil, C-reactive protein, and neutrophil-to-lymphocyte ratio were measured in all subjects before the start of antimicrobial chemotherapy to the infected ones.
Results
Both the serum and ascetic fluid amyloid and also, CRP were significantly higher in patients infected with …
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R Badawi, MN Asghar, S Abd-Elsalam, SA Elshweikh… - Anti-Inflammatory & Anti-Allergy Agents in Medicinal …, 2020