作者
Qing Ye, Biyao Zou, Yee Hui Yeo, Jie Li, Daniel Q Huang, Yuankai Wu, Hongli Yang, Chuanli Liu, Leslie Y Kam, Xiang Xuan Eunice Tan, Nicholas Chien, Sam Trinh, Linda Henry, Christopher Donald Stave, Tetsuya Hosaka, Ramsey C Cheung, Mindie H Nguyen
发表日期
2020/8/1
来源
The lancet Gastroenterology & hepatology
卷号
5
期号
8
页码范围
739-752
出版商
Elsevier
简介
Background
Although non-alcoholic fatty liver disease (NAFLD) is commonly associated with obesity, it is increasingly being identified in non-obese individuals. We aimed to characterise the prevalence, incidence, and long-term outcomes of non-obese or lean NAFLD at a global level.
Methods
For this systematic review and meta-analysis, we searched PubMed, Embase, Scopus, and the Cochrane Library from inception to May 1, 2019, for relevant original research articles without any language restrictions. The literature search and data extraction were done independently by two investigators. Primary outcomes were the prevalence of non-obese or lean people within the NAFLD group and the prevalence of non-obese or lean NAFLD in the general, non-obese, and lean populations; the incidence of NAFLD among non-obese and lean populations; and long-term outcomes of non-obese people with NAFLD. We also …
学术搜索中的文章
Q Ye, B Zou, YH Yeo, J Li, DQ Huang, Y Wu, H Yang… - The lancet Gastroenterology & hepatology, 2020