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ContextTransplantation has become the therapy of choice for patients with organ failure. However, the low rate of consent by families of donor-eligible patients is a major limiting factor in the success of organ transplantation.ObjectiveTo explore factors associated with the decision to donate among families of potential solid organ donors.Design and SettingData collection via chart reviews, telephone interviews with health care practitioners (HCPs) or organ procurement organization (OPO) staff, and face-to-face interviews with family for all donor-eligible deaths at 9 trauma hospitals in southwestern Pennsylvania and northeastern Ohio from 1994 to 1999.ParticipantsFamily members, HCPs, and OPO staff involved in the donation decision for 420 donor-eligible patients.Main Outcome MeasureFactors associated with family decision to donate or not donate organs for transplantation.ResultsA total of 238 of the 420 …