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New theories on psychological and emotional disorders reveal a bio-psychosocial causality as being determinant in the occurrence and development of such disorders. Therefore, therapeutic methods can no longer be limited to separate interventions, only through medication, psychotherapy or social support. This paper assesses the degree of association between two of the personality dimensions, Agreeability and Emotional Stability (as measured by DECAS; Sava, 2008), before and after combined therapy consisting of psychotherapy and an antidepressant (Escitalopram), within a sample of patients (N=32) suffering from generalised anxiety disorder occurring in comorbidity with obsessive-compulsive personality disorder. The results obtained indicate the fact that the association of Agreeability and Emotional Stability in the pre-treatment stage is moderate (r = .43), but it becomes stronger following combined …