作者
Amir Hadi, Hamed Mohammadi, Maryam Miraghajani, Ehsan Ghaedi
发表日期
2019/8/22
来源
Critical reviews in food science and nutrition
卷号
59
期号
15
页码范围
2494-2505
出版商
Taylor & Francis
简介
Objective: We systematically reviewed available randomized clinical trials (RCTs) to elucidate the overall effects of synbiotic supplementation in patients with nonalcoholic fatty liver disease (NAFLD).
Methods: PubMed, Scopus, ISI Web of science and Google Scholar were searched up to December, 2017. All RCTs using synbiotic supplements to treat NAFLD included in this systematic review and meta-analysis. Mean Difference (MD) was pooled using a random-effects model.
Results: Eleven eligible databases from seven RCTs were identified for the present meta-analysis. Our results showed that synbiotic supplementation can decrease body weight, fasting blood sugar, insulin, low density lipoprotein cholesterol, total cholesterol, triglyceride, high-sensitivity C-reactive protein, tumor necrosis factor alpha, alanine transaminase and aspartate transaminase levels among patients with NAFLD. In contrast, synbiotic did …
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A Hadi, H Mohammadi, M Miraghajani, E Ghaedi - Critical reviews in food science and nutrition, 2019