作者
Ann Klopp, Benjamin D Smith, Kaled Alektiar, Alvin Cabrera, Antonio L Damato, Beth Erickson, Gini Fleming, David Gaffney, Kathryn Greven, Karen Lu, David Miller, David Moore, Daniel Petereit, Tracey Schefter, William Small Jr, Catheryn Yashar, Akila N Viswanathan
发表日期
2014/5/1
来源
Practical radiation oncology
卷号
4
期号
3
页码范围
137-144
出版商
Elsevier
简介
Purpose
To present evidence-based guidelines for adjuvant radiation in the treatment of endometrial cancer.
Methods and materials
Key clinical questions to be addressed in this evidence-based guideline on endometrial cancer were identified. A comprehensive literature review was performed to identify studies that included no adjuvant therapy, or pelvic radiation or vaginal brachytherapy with or without systemic chemotherapy. Outcomes included local control, survival rates, and overall assessment of quality of life.
Results
Patients with grade 1 or 2 cancers with either no invasion or < 50% myometrial invasion (MI), especially when no other high risk features are present, can be safely observed after hysterectomy. Vaginal cuff brachytherapy is as effective as pelvic radiation therapy at preventing vaginal recurrence for patients with grade 1 or 2 cancers with ≥ 50% MI or grade 3 tumors with < 50% MI. Patients with …
学术搜索中的文章
A Klopp, BD Smith, K Alektiar, A Cabrera, AL Damato… - Practical radiation oncology, 2014