查看文章

Breast cancer is a heterogenic disease that comprises of various morphologies with intrinsic subtypes and is principally responsible for casualties among female cancer patients. Triple-negative breast cancer (TNBC) is the most aggressive subtype with a high probability of relapsing, hence successful treatment can be quite challenging. The pathogenesis of TNBC remains ambiguous and the identification of dependable biomarkers for its early diagnosis is crucial to design a strategy for therapeutic armamentarium.

To clarify the folate-dependent mechanism of action causing cell death and to unravel the potential biomarkers of TNBC to defeat this consequential public health burden.

The MTT assay and the morphological examination via microscopy were carried out to examine the viability of the cells upon the administration of the blank folate-conjugated cyclodextrin nanoparticles …