查看文章

Vol. 24 No. 4 Oct.-Dec. 2002 650 to those of standard and control groups. This finding suggests that liver injury did not occur in treated mice. The relative liver weights of treated mice were not different (p> 0.05) from those of control male mice, while lower relative liver weights (p< 0.05) were obtained in female treated and standard groups when compared to their control. Normal number and growth rate of offspring were obtained in DFII-and DFI-treated and control female groups. Subchronic toxicity in this study suggests that polysaccharide gel from fruit-hulls of durian at oral doses of 0.25 and 0.5 g/kg/d could be consumed safely for a long period of 60-100 days in male and female mice.