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The aim of the present study was to investigate the effects of polyphenols extracted from chestnut and olive mill wastewater on growth performance, skin mucus, and serum immune parameters as well as antioxidant defence in common carp (Cyprinus carpio L.) juveniles. For this purpose, common carp juveniles (15 ± 0.3 g) were fed experimental diets containing different levels 0 (control), 0.05, 0.1, and 0.2% of polyphenols for 8 weeks. At the end of the trial, the growth parameters, haematological parameters, serum total protein, total immunoglobulin, lysozyme activity, and total antioxidant activity were measured in mucus and serum samples. The growth parameters revealed a significant increase in fish fed polyphenols containing diets compared to the control group (P < 0.05). In addition, the feed conversion ratio of fish fed polyphenols was significantly decreased (P < 0.05) compared to the control group …