作者
Jong-Eun Kim, Seong-Su Kang, Kyung-Hee Choi, June-Sung Shim, Chang-Mo Jeong, Sang-Wan Shin, Jung-Bo Huh
发表日期
2013/6/1
期刊
Oral surgery, oral medicine, oral pathology and oral radiology
卷号
115
期号
6
页码范围
e24-e31
出版商
Mosby
简介
OBJECTIVES
The aim of this study was to evaluate the effect of anodized implants coated with combined rhBMP-2 and recombinant human vascular endothelial growth factors (rhVEGFs) on vertical bone regeneration in the marginal portion of the peri-implant.
STUDY DESIGN
Supra-alveolar defects were created in 3 male beagle dogs. Each animal received 8 implants that were either coated with a single growth factor (rhBMP-2) or combined growth factors (rhBMP-2 + rhVEGF), or an anodized implant (the control group). The amount of the vertical bone regeneration, the bone-implant contact, and the intrathread bone density were investigated using histomorphometric analysis at 8 weeks.
RESULTS
The bone morphogenetic protein (BMP) group and the BMP-VEGF group showed vertical alveolar bone regeneration and enhanced bone-implant contact in the microthread compared with the control group (P < .05 …
学术搜索中的文章
JE Kim, SS Kang, KH Choi, JS Shim, CM Jeong… - Oral surgery, oral medicine, oral pathology and oral …, 2013