作者
Nuria Sanchez Clemente, Cesar Ugarte-Gil, Nelson Solorzano, Ciro Maguiña, David Moore
发表日期
2016/3/18
期刊
PLoS One
卷号
11
期号
3
页码范围
e0150525
出版商
Public Library of Science
简介
Background
Bartonellosis affects small Andean communities in Peru, Colombia and Ecuador. Research in this area has been limited.
Methods
Retrospective review of 191 cases of bartonellosis managed in Caraz District Hospital, Peru, during the last outbreak (2003).
Results
The majority of cases (65%) were 14 years old and younger. There was a peak in acute cases after the rainy season; chronic cases presented more constantly throughout the year. The sensitivity of blood smear against blood culture in acute disease was 25%. The most commonly used treatment for chronic disease was rifampicin; chloramphenicol was used to treat most acute cases. Complications arose in 6.8% and there were no deaths.
Conclusions
Diagnostic and treatment algorithms for acute and chronic bartonellosis have been developed without a strong evidence base. Preparation of ready-to-go operational research protocols for future outbreaks would strengthen the evidence base for diagnostic and treatment strategies and enhance opportunities for control.
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