作者
Anna K Coussens, Syed MA Zaidi, Brian W Allwood, Puneet K Dewan, Glenda Gray, Mikashmi Kohli, Tamara Kredo, Ben J Marais, Guy B Marks, Leo Martinez, Morten Ruhwald, Thomas J Scriba, James A Seddon, Phumeza Tisile, Digby F Warner, Robert J Wilkinson, Hanif Esmail, Rein MGJ Houben, David Alland, Marcel A Behr, Busisiwe B Beko, Erlina Burhan, Gavin Churchyard, Frank Cobelens, Justin T Denholm, Ryan Dinkele, Jerrold J Ellner, Razia Fatima, Kate A Haigh, Mark Hatherill, Katherine C Horton, Emily A Kendall, Palwasha Y Khan, Peter MacPherson, Stephanus T Malherbe, Vidya Mave, Simon C Mendelsohn, Munyaradzi Musvosvi, Elisa Nemes, Adam Penn-Nicholson, Dharanidharan Ramamurthy, Molebogeng X Rangaka, Suvanand Sahu, Alvaro Schwalb, Divya K Shah, Dylan Sheerin, Donald Simon, Adrie JC Steyn, Nguyen Thu Anh, Gerhard Walzl, Charlotte L Weller, Caroline ML Williams, Emily B Wong, Robin Wood, Yingda L Xie, Siyan Yi
发表日期
2024/6/1
来源
The Lancet Respiratory Medicine
卷号
12
期号
6
页码范围
484-498
出版商
Elsevier
简介
The current active–latent paradigm of tuberculosis largely neglects the documented spectrum of disease. Inconsistency with regard to definitions, terminology, and diagnostic criteria for different tuberculosis states has limited the progress in research and product development that are needed to achieve tuberculosis elimination. We aimed to develop a new framework of classification for tuberculosis that accommodates key disease states but is sufficiently simple to support pragmatic research and implementation. Through an international Delphi exercise that involved 71 participants representing a wide range of disciplines, sectors, income settings, and geographies, consensus was reached on a set of conceptual states, related terminology, and research gaps. The International Consensus for Early TB (ICE-TB) framework distinguishes disease from infection by the presence of macroscopic pathology and defines two …
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AK Coussens, SMA Zaidi, BW Allwood, PK Dewan… - The Lancet Respiratory Medicine, 2024