作者
Abigail L Lind, Yvonne YY Lai, Yulia Mostovoy, Alisha K Holloway, Alessio Iannucci, Angel CY Mak, Marco Fondi, Valerio Orlandini, Walter L Eckalbar, Massimo Milan, Michail Rovatsos, Ilya G Kichigin, Alex I Makunin, Martina Johnson Pokorná, Marie Altmanová, Vladimir A Trifonov, Elio Schijlen, Lukáš Kratochvíl, Renato Fani, Petr Velenský, Ivan Rehák, Tomaso Patarnello, Tim S Jessop, James W Hicks, Oliver A Ryder, Joseph R Mendelson III, Claudio Ciofi, Pui-Yan Kwok, Katherine S Pollard, Benoit G Bruneau
发表日期
2019/8
期刊
Nature ecology & evolution
卷号
3
期号
8
页码范围
1241-1252
出版商
Nature Publishing Group UK
简介
Monitor lizards are unique among ectothermic reptiles in that they have high aerobic capacity and distinctive cardiovascular physiology resembling that of endothermic mammals. Here, we sequence the genome of the Komodo dragon Varanus komodoensis, the largest extant monitor lizard, and generate a high-resolution de novo chromosome-assigned genome assembly for V. komodoensis using a hybrid approach of long-range sequencing and single-molecule optical mapping. Comparing the genome of V. komodoensis with those of related species, we find evidence of positive selection in pathways related to energy metabolism, cardiovascular homoeostasis, and haemostasis. We also show species-specific expansions of a chemoreceptor gene family related to pheromone and kairomone sensing in V. komodoensis and other lizard lineages. Together, these evolutionary signatures of adaptation reveal the …
学术搜索中的文章
AL Lind, YYY Lai, Y Mostovoy, AK Holloway, A Iannucci… - Nature ecology & evolution, 2019