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All behaviors’ that satisfy a person's biological needs and desires are considered sexual behaviors. Despite the fact that sexual behavior and expression are universal to all animals, especially humans, the context in which the behaviors are expressed may make it risky or even dangerous. High risk sexual behaviors’ and substance use disorders are frequently been linked. This study's main goal is to investigate the relationship between substance use by Men and their participation in high risk sexual behaviors. In the current study data were taken from NFHS 5 (2019–2021) and methods like Pearson's chi-squared test, bivariate and multivariate binary logistic regression models were used to established the relationship that risky sexual behavior is a consequence of substances use. Result revealed that Men’s alcohol consumption in daily basis is strongly associated with premature sex (AOR: 1.05; 95%CI: 1.08–1.26 …