作者
Victor M Lu, Anshit Goyal, Christopher S Graffeo, Avital Perry, Terry C Burns, Ian F Parney, Alfredo Quinones-Hinojosa, Kaisorn L Chaichana
发表日期
2019/7/1
来源
World neurosurgery
卷号
127
页码范围
31-37
出版商
Elsevier
简介
Background
Although reoperation likely confers survival benefit for glioblastoma, whether the extent of resection (EOR) of the reoperation affects survival outcome has yet to be thoroughly evaluated in the current temozolomide (TMZ) era. The aim of this meta-analysis was to pool the current literature and evaluate the prognostic significance of reoperation EOR for glioblastoma recurrence in the current TMZ era.
Methods
Searches of 7 electronic databases from inception to January 2019 were conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. There were 1203 articles identified for screening. Prognostic hazard ratios (HRs) for overall survival (OS) derived from multivariate regression analysis were analyzed using meta-analysis of proportions.
Results
Nine individual studies satisfied all selection criteria, describing survival in 1507 patients with glioblastoma, including …
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VM Lu, A Goyal, CS Graffeo, A Perry, TC Burns… - World neurosurgery, 2019