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The efficacy of artesunate in the treatment of urinary schistosomiasis was assessed among school children aged 5-16 years. Urine samples from 367 primary school children were examined for ova of Schistosoma haematobium. Using standard parasitological procedures (filtration method), S. haematobium ova was found in the urine samples of 29(7.9%) pupils. High infection rates of 16.0% and 13.2% were recorded in two primary schools with an overall egg output of 10.55 eggs/10 mls urine (geometric mean). The prevalence was higher in the males (10.10%) than in the females (5.0%) and among the 12-16 years age group (15.1; p≤0.05). Infected pupils who reported for treatment were given oral dose of artesunate (4 mg/kg/day) for 3 days. When the treated children were examined 2 weeks post treatment, the intensity reduced to 1.59 eggs/10 ml urine and the drug had an 85.12% egg reduction and …