作者
Francois-Pierre Mongeon, Walid Ben Ali, Paul Khairy, Ismail Bouhout, Judith Therrien, Rachel M Wald, Frederic Dallaire, Pierre-Luc Bernier, Nancy Poirier, Annie Dore, Candice Silversides, Ariane Marelli
发表日期
2019/12/1
来源
Canadian Journal of Cardiology
卷号
35
期号
12
页码范围
1772-1783
出版商
Elsevier
简介
Background
There is no systematic evidence review of the long-term results of surgical pulmonary valve replacement (PVR) dedicated to adults with repaired tetralogy of Fallot (rTOF) and pulmonary regurgitation.
Methods
Our primary objective was to determine whether PVR reduced long-term mortality in adults with rTOF compared with conservative therapy. Secondary objectives were to determine the postoperative incidence rate of death, the changes in functional capacity and in right ventricular (RV) volumes and ejection fraction after PVR, and the postoperative incidence rate of sustained ventricular arrhythmias. A systematic search of multiple databases for studies was conducted without limits.
Results
No eligible randomized controlled trial or cohort study compared outcomes of PVR and conservative therapy in adults with rTOF. We selected 10 cohort studies (total 657 patients) reporting secondary outcomes …
学术搜索中的文章
FP Mongeon, WB Ali, P Khairy, I Bouhout, J Therrien… - Canadian Journal of Cardiology, 2019