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In the 21st century, the Pharma market has changed significantly. The companies worldwide are forced to reconsider their business priorities and strategies in order to handle the uncertainty, volatility and complexity. In line with this development, the companies in pharmaceutical market have realized the importance of effective supply chain management. This review article aims to discuss the importance of supply chain management within pharmaceutical and radiopharmaceutical industries. After introducing several basic concepts in supply chain research field, we will discuss the differences of supply chain between Pharma/radiopharma industries and other industries and the challenges faced in the focus industries. Different states of art supply chain management models, developed by several major companies in both industries, are evaluated in order to support the future’s successful businesses.