作者
Cristiane Maria Galvão Barbosa, Mario Terra-Filho, André Luis Pereira de Albuquerque, Dante Di Giorgi, Cesar Grupi, Carlos Eduardo Negrao, Maria Urbana Pinto Brandão Rondon, Daniel Godoy Martinez, Tania Marcourakis, Fabiana Almeida dos Santos, Alfésio Luís Ferreira Braga, Dirce Maria Trevisan Zanetta, Ubiratan de Paula Santos
发表日期
2012/9/27
卷号
7
期号
9
页码范围
e46142
出版商
Public Library of Science
简介
Background
Brazil is the world's largest producer of sugarcane. Harvest is predominantly manual, exposing workers to health risks: intense physical exertion, heat, pollutants from sugarcane burning.
Design
Panel study to evaluate the effects of burnt sugarcane harvesting on blood markers and on cardiovascular system.
Methods
Twenty-eight healthy male workers, living in the countryside of Brazil were submitted to blood markers, blood pressure, heart rate variability, cardiopulmonary exercise testing, sympathetic nerve activity evaluation and forearm blood flow measures (venous occlusion plethysmography) during burnt sugarcane harvesting and four months later while they performed other activities in sugar cane culture.
Results
Mean participant age was 31±6.3 years, and had worked for 9.8±8.4 years on sugarcane work. Work during the harvest period was associated with higher serum levels of Creatine Kinase – 136.5 U/L (IQR: 108.5–216.0) vs. 104.5 U/L (IQR: 77.5–170.5), (p = 0.001); plasma Malondialdehyde–7.5±1.4 µM/dl vs. 6.9±1.0 µM/dl, (p = 0.058); Glutathione Peroxidase – 55.1±11.8 Ug/Hb vs. 39.5±9.5 Ug/Hb, (p<0.001); Glutathione Transferase– 3.4±1.3 Ug/Hb vs. 3.0±1.3 Ug/Hb, (p = 0.001); and 24-hour systolic blood pressure – 120.1±10.3 mmHg vs. 117.0±10.0 mmHg, (p = 0.034). In cardiopulmonary exercise testing, rest-to-peak diastolic blood pressure increased by 11.12 mmHg and 5.13 mmHg in the harvest and non-harvest period, respectively. A 10 miliseconds reduction in rMSSD and a 10 burst/min increase in sympathetic nerve activity …
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