作者
Jan A Staessen, Geert Byttebier, Frank Buntinx, Hilde Celis, Eoin T O'Brien, Robert Fagard
发表日期
1997/10/1
期刊
Jama
卷号
278
期号
13
页码范围
1065-1072
出版商
American Medical Association
简介
Context
—Ambulatory blood pressure (ABP) monitoring is used increasingly in clinical practice, but how it affects treatment of blood pressure has not been determined.
Objective
—To compare conventional blood pressure (CBP) measurement and ABP measurement in the management of hypertensive patients.
Design
—Multicenter randomized, parallel-group trial.
Setting
—Family practices and outpatient clinics at regional and university hospitals.
Participants
—A total of 419 patients (-18 years), whose untreated diastolic blood pressure (DBP) on CBP measurement averaged 95 mm Hg or higher, randomized to CBP or ABP arms.
Interventions
—Antihypertensive drug treatment was adjusted in a stepwise fashion based on either the average daytime (from 10 am to 8 pm) ambulatory DBP (n=213) or the average of 3 sitting DBP readings (n=206). If the DBP guiding treatment was above (>89 mm Hg), at (80-89 mm Hg), or …
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