作者
Jessica JM Barnes, Angela J Dean, L Sanjay Nandam, Redmond G O'Connell, Mark A Bellgrove
发表日期
2011/6/15
来源
Biological psychiatry
卷号
69
期号
12
页码范围
e127-e143
出版商
Elsevier
简介
Executive control processes, such as sustained attention, response inhibition, and error monitoring, allow humans to guide behavior in appropriate, flexible, and adaptive ways. The consequences of executive dysfunction for humans can be dramatic, as exemplified by the large range of both neurologic and neuropsychiatric disorders in which such deficits negatively affect outcome and quality of life. Much evidence suggests that many clinical disorders marked by executive deficits are highly heritable and that individual differences in quantitative measures of executive function are strongly driven by genetic differences. Accordingly, intense research effort has recently been directed toward mapping the genetic architecture of executive control processes in both clinical (e.g., attention-deficit/hyperactivity disorder) and nonclinical populations. Here we review the extant literature on the molecular genetic correlates of …
引用总数
20112012201320142015201620172018201920202021202220232024612122525281619147910144
学术搜索中的文章