作者
Aria Fallah, Evan Lewis, George M Ibrahim, Olivia Kola, Chi‐Hong Tseng, William B Harris, Jia‐Shu Chen, Kao‐Min Lin, Li‐Xin Cai, Qing‐Zhu Liu, Jiu‐Luan Lin, Wen‐Jing Zhou, Gary W Mathern, Matthew D Smyth, Brent R O'Neill, Roy WR Dudley, John Ragheb, Sanjiv Bhatia, Daniel Delev, Georgia Ramantani, Josef Zentner, Anthony C Wang, Christian Dorfer, Martha Feucht, Thomas Czech, Robert J Bollo, Galymzhan Issabekov, Hongwei Zhu, Mary Connolly, Paul Steinbok, Jian‐Guo Zhang, Kai Zhang, Eveline Teresa Hidalgo, Howard L Weiner, Lily Wong‐Kisiel, Samuel Lapalme‐Remis, Manjari Tripathi, Poodipedi Sarat Chandra, Walter Hader, Feng‐Peng Wang, Yi Yao, Pierre‐Olivier Champagne, Tristan Brunette‐Clément, Qiang Guo, Shao‐Chun Li, Marcelo Budke, Maria Angeles Pérez‐Jiménez, Christian Raftopoulos, Patrice Finet, Pauline Michel, Karl Schaller, Martin N Stienen, Valentina Baro, Christian Cantillano Malone, Juan Pociecha, Noelia Chamorro, Valeria L Muro, Marec von Lehe, Silvia Vieker, Chima Oluigbo, William D Gaillard, Mashael Al‐Khateeb, Faisal Al Otaibi, Niklaus Krayenbühl, Jeffrey Bolton, Phillip L Pearl, Alexander G Weil
发表日期
2021/11
期刊
Epilepsia
卷号
62
期号
11
页码范围
2707-2718
简介
Objective
This study was undertaken to determine whether the vertical parasagittal approach or the lateral peri‐insular/peri‐Sylvian approach to hemispheric surgery is the superior technique in achieving long‐term seizure freedom.
Methods
We conducted a post hoc subgroup analysis of the HOPS (Hemispheric Surgery Outcome Prediction Scale) study, an international, multicenter, retrospective cohort study that identified predictors of seizure freedom through logistic regression modeling. Only patients undergoing vertical parasagittal, lateral peri‐insular/peri‐Sylvian, or lateral trans‐Sylvian hemispherotomy were included in this post hoc analysis. Differences in seizure freedom rates were assessed using a time‐to‐event method and calculated using the Kaplan–Meier survival method.
Results
Data for 672 participants across 23 centers were collected on the specific hemispherotomy approach. Of these, 72 (10 …
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A Fallah, E Lewis, GM Ibrahim, O Kola, CH Tseng… - Epilepsia, 2021
